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题名: Probabilistic Framework for Assessing the Potential Human Risk of Heavy Metals in Chinese Herbal Medicine.
作者: Min-Pei Ling
Sze-Ting Choi
Jui-Ting Chang
Hsu-Hui Cheng
贡献者: 國立臺灣海洋大學:食品科學系
关键词: Health Risk Assessment
Heavy metal
Traditional Chinese Medicine
日期: 2018-11
上传时间: 2020-06-22T06:22:09Z
出版者: Journal of Environmental Science, Toxicology and Food Technology
摘要: ABSTRACT:
Chinese herbal medicine (CHM), widely used therapeutic agents for various purposes, contains abundant vitamins and specific compounds. Heavy metals in CHM may have adverse health effects. Heavymetal concentrations of inorganic arsenic (iAs), cadmium (Cd), copper (Cu), mercury (Hg), and lead (Pb) in CHM prescriptions are obtained from the Taiwan Food and Drug Administration and the Herbal Pharmacopeia. The average daily intake of the Taiwanese population above 18 years old is used in the exposure assessment. In conclusion, the non-carcinogenic risk posed by iAs, Cd, Cu, Hg and Pb are within the acceptable safety range for human health, and the carcinogenic risk posed by iAs is also acceptable. Only the 95th percentile (P95) with prescription “Blood/Painkiller” (BP) of Hg is higher than 1, with a value of 1.7. The safety of CHM can be improved by Good Agricultural Practice (GAP) and Good Manufacture Practice (GMP), and by reducing the heavy-metal levels in the environment as possible. Further study can focus on vulnerable groups such as the elderly, children, pregnant or high-risk groups (patients using CHM in the long term). Keyword:Health Risk Assessment, Heavy metal, Traditional
關聯: 12(9) pp 59-73
URI: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/52992
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