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Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/52992

Title: Probabilistic Framework for Assessing the Potential Human Risk of Heavy Metals in Chinese Herbal Medicine.
Authors: Min-Pei Ling
Sze-Ting Choi
Jui-Ting Chang
Hsu-Hui Cheng
Contributors: 國立臺灣海洋大學:食品科學系
Keywords: Health Risk Assessment
Heavy metal
Traditional Chinese Medicine
Date: 2018-11
Issue Date: 2020-06-22T06:22:09Z
Publisher: Journal of Environmental Science, Toxicology and Food Technology
Abstract: ABSTRACT:
Chinese herbal medicine (CHM), widely used therapeutic agents for various purposes, contains abundant vitamins and specific compounds. Heavy metals in CHM may have adverse health effects. Heavymetal concentrations of inorganic arsenic (iAs), cadmium (Cd), copper (Cu), mercury (Hg), and lead (Pb) in CHM prescriptions are obtained from the Taiwan Food and Drug Administration and the Herbal Pharmacopeia. The average daily intake of the Taiwanese population above 18 years old is used in the exposure assessment. In conclusion, the non-carcinogenic risk posed by iAs, Cd, Cu, Hg and Pb are within the acceptable safety range for human health, and the carcinogenic risk posed by iAs is also acceptable. Only the 95th percentile (P95) with prescription “Blood/Painkiller” (BP) of Hg is higher than 1, with a value of 1.7. The safety of CHM can be improved by Good Agricultural Practice (GAP) and Good Manufacture Practice (GMP), and by reducing the heavy-metal levels in the environment as possible. Further study can focus on vulnerable groups such as the elderly, children, pregnant or high-risk groups (patients using CHM in the long term). Keyword:Health Risk Assessment, Heavy metal, Traditional
Relation: 12(9) pp 59-73
URI: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/52992
Appears in Collections:[食品科學系] 期刊論文

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