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Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/51133

Title: Inhibition of SARS-CoV replication by niclosamide
Authors: Wu CJ1
Jan JT
Chen CM
Hsieh HP
Hwang DR
Liu HW
Liu CY
Huang HW
Chen SC
Hong CF
Lin RK
Chao YS
Hsu JT
Contributors: 國立臺灣海洋大學:食品科學系
Date: 2004-07
Issue Date: 2018-11-13T08:43:40Z
Publisher: Antimicrobial Agents and Chemotherapy
Abstract: Abstract: Antiviral agents are urgently needed to fight severe acute respiratory syndrome (SARS). We showed that niclosamide, an existing antihelminthic drug, was able to inhibit replication of a newly discovered coronavirus, SARS-CoV; viral antigen synthesis was totally abolished at a niclosamide concentration of 1.56 microM, as revealed by immunoblot analysis. Thus, niclosamide represents a promising drug candidate for the effective treatment of SARS-CoV infection.
Relation: 48(7) pp.2693-2696
URI: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/51133
Appears in Collections:[食品科學系] 期刊論文

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