Abstract: In this study, the complete mitogenome sequence of variegated lizardfish Synodus variegatus (Lacepède, 1803) (Perciformes, Synodontidae) has been amplified and sequenced employing the long polymerase chain reaction method. The mitogenome, consisting of 16,448 base pairs (bp), had the typical vertebrate mitochondrial gene arrangement, including 13 protein-coding, 22 transfer RNAs, 2 ribosomal RNAs genes and a noncoding control region (CR). The CR of 830 bp length is rather compact and located between tRNAPro and tRNAPhe. The overall base composition of Myxocyprinus asiaticus is 26.36% for A, 27.69% for C, 26.99% for T and 18.95% for G, with a slight AT bias of 53.36%. The complete mitogenome may provide important DNA molecular data for further phylogenetic analyses for higher taxa of teleost fishes, especially for the fishes of order Aulopiformes.