Abstract: Biomedical coatings are used to promote the wear resistance and the biocompatibility
of a mechanical heart valve. An orbital shaking test was proposed to assess the durability of the
coatings by the amount material eroded by the surrounding fluid. However, there is still a lack of
understanding with regards to the shaker’s rotating conditions and the corresponding physiological
condition. This study implemented numerical simulations by establishing a fluid dynamic model
to evaluate the intensity of the shear stress under various rotating speeds and diameters of the
shaker. The results are valuable to conduct in vitro tests for estimating the performance of biomedical
coatings under real hemodynamic conditions and can be applied to other fluid-contact implants.