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Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/47429

Title: The One-Dimensional Dynamics and Transport of DNA Molecules in a Quasi-Two-Dimensional Nanoslit
Authors: W. S. Fann
Po-Keng Lin
Keng-hui Lin
Chi-Cheng Fu
K.-C. Lee
Pei-Kuen Wei
Woei-Wu Pai
Pei-Hsi Tsao
Y.-L. Chen
Contributors: 國立臺灣海洋大學:光電科學研究所
Date: 2009-03
Issue Date: 2018-07-23
Publisher: Macromolecules
Abstract: Abstract: We report an unusual phenomena of attraction between DNA and the sidewall of a two-dimensional (2d) glass nanoslit with height, h, less than the Kuhn length l(K). The DNA molecules are stretched and diffuse along the wall. The scaling analysis reveals that the wall-bound DNA molecules exhibit one-dimensional (1d) diffusion. A modified blob model is able to predict the chain extension down to 30 nm, well into the subpersistence length regime where the chain deflection length should be considered. This discrepancy may be due to the partially bound confinement of chains near the sidewall. In contrast, the scaling analysis of DNA molecules far from the sidewall exhibit 2d dynamics that can be described by de Gennes and Odijk model for h > l(K) and h < l(K) respectively. We further apply the unusual wall attraction to trap and stretch DNA molecules around posts in a nanoslit. We demonstrate that the DNA molecules exhibit trapping-escaping movement, and they can be transported from post to post with an electric field.
Relation: 42(5) pp.1770-1774
URI: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/47429
Appears in Collections:[Institute of Optoelectronic Sciences] Periodical Articles

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