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Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/47370

Title: Visualization of biosensors using enhanced surface plasmon resonances in capped silver nanostructures
Authors: Pei-Kuen Wei
Kuang-Li Lee
Meng-Lin You
Cheng-Lin Tsai
Chia-Yu Hung
Shu-Yi Hsieha
Contributors: 國立臺灣海洋大學:光電科學研究所
Date: 2016-02
Issue Date: 2018-07-17T02:46:56Z
Publisher: Analyst
Abstract: Abstract: We propose a method and optical design for direct visualization of label-free detection. The system, similar to a tiny spectral analyzer, is composed of a nanostructure-based surface plasmon resonance chip, linear polarizer and 532 nm laser light source. The full-width-at-half-maximum bandwidths of the enhanced surface plasmon resonances are about 5 nm. The distribution of the transmitted light from these arrays comprises a spectral image on the chip. The qualitative and quantitative analyses of the analyte can be conducted by observing the spot shift on the chip. We tested the sensing capability of the chip. The detectable surface mass density with the naked eye is about 0.476 μg cm−2. In addition, antigen–antibody interaction experiments are conducted to verify the surface binding measurements. A monolayer protein attached on the chip can be directly observed and the concentration levels of the analyte can be estimated with the naked eye. Such plasmonic biochips can benefit sensing applications in point-of-care diagnostics.
Relation: 141(3) pp.974-980
URI: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/47370
Appears in Collections:[光電科學研究所] 期刊論文

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