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题名: Imaging Cells in Tissues with Refractive Index Radiology
作者: G.M. Chow
Y. Hwu
W. L. Tsai
H. M. Chang
H. I. Yeh
P.C. Hsu
Y. C. Yang
Y. T. Su
贡献者: 國立臺灣海洋大學:光電科學研究所
日期: 2004-12
上传时间: 2018-07-16T08:31:59Z
出版者: Biophysical Journal
摘要: Abstract: Can individual cells, including live cells, be imaged using hard x rays? Common wisdom until now required sophisticated staining techniques for this task. We show instead that individual cells and cell details can be detected in culture solution and tissues with no staining and no other contrast-enhancing preparation. The sample examined can be much thicker than for many other microscopy techniques without sacrificing the capability to resolve cells. The key factor in our approach is the use of a coherent synchrotron source and of contrast mechanisms based on the refractive index. The first successful tests were conducted on a variety of cell systems including skin and internal leaf cells, mouse neurons, rabbit fibroblast cells, and human tumor cells.
關聯: 87(6)
显示于类别:[光電科學研究所] 期刊論文


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