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題名: X-ray imaging of tumor growth in live mice by detecting gold-nanoparticle-loaded cells
作者: G. Margaritondo
Chia-Chi Chien
Hsiang-Hsin Chen
Sheng-Feng Lai
Y. Hwu
C. S. Yang
Y. Chu
Cyril Petibois
貢獻者: 國立臺灣海洋大學:光電科學研究所
日期: 2012-08
上傳時間: 2018-07-09T02:48:46Z
出版者: Scientific Reports
摘要: Abstract: We show that sufficient concentrations of gold nanoparticles produced by an original synthesis method in EMT-6 and CT-26 cancer cells make it possible to detect the presence, necrosis and proliferation of such cells after inoculation in live mice. We first demonstrated that the nanoparticles do not interfere with the proliferation process. Then, we observed significant differences in the tumor evolution and the angiogenesis process after shallow and deep inoculation. A direct comparison with pathology optical images illustrates the effectiveness of this approach.
顯示於類別:[光電科學研究所] 期刊論文


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