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Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/46099

Title: Mosquito larvicidal activity of Broussonetia papyrifera compound marmesin by blocking protein AESCP-2, docking strategies, and combined effect of copepod Megacyclops formosanus against dengue vector Aedes aegypti (Diptera: Culicidae)
Authors: Kandasamy Kalimuthu
Chia-Hsiang Wang
Shiu-Mei Liu
Li-Chun Tseng
Kadarkarai Murugan
Jiang-Shiou Hwang
Contributors: 國立臺灣海洋大學:海洋生物研究所
Keywords: larvicidal
Broussonetia papyrifera
Aedes aegypti
sterol carrier protein-2
Date: 2013
Issue Date: 2018-05-02T02:34:51Z
Publisher: Journal of Marine Science and Technology
Abstract: Abstract: Mosquito-borne diseases that have an economic impact create losses in commercial and labor outputs, particularly in countries with tropical and subtropical climates. The emergence of resistance to synthetic insecticides is a challenge to mosquito control. Cyclopoid copepods are important predators in many aquatic ecosystems and have been successfully used as biological agents to control mosquito larvae. For this study, we examined the larvicidal activity of the copepod Megacyclops formosanus in combination with the compound marmesin (which was purified from the methanol crude extract of the plant stem bark of Broussonetia papyrifera) against Aedes aegypti larvae. Their larvicidal activity and in silico docking analysis regarding the inhibition of the binding cholesterol sterol carrier protein-2 (AeSCP-2) against A. aegypti were evaluated. The significant larvicidal potential was recorded after the marmesin plant compound treatment against the dengue vector A. aegypti. Larval mortality was observed after 24 h of exposure. The LC50 and LC90 of marmesin against the first to fourth instar larvae and pupae were 0.104
Relation: 21 pp.308-315
URI: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/46099
Appears in Collections:[海洋生物研究所] 期刊論文

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