National Taiwan Ocean University Institutional Repository:Item 987654321/44265
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 26988/38789
造访人次 : 2352227      在线人数 : 30
RC Version 4.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 进阶搜寻

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/44265

题名: RNA-seq Coverage Effects on Biological Pathways and GO Tag Clouds
作者: Chien-Ming Chen
Tsan-Huang Shih
Tun-Wen Pai
Zhen-Long Liu
Margaret Dah-Tsyr Chang
贡献者: 國立臺灣海洋大學:資訊工程學系
NTOU:Department of Computer Science and Engineering
关键词: Gene Ontology
temporal pathway
RNA-seq
cross-strain comparison
日期: 2012-08
上传时间: 2017-11-20T08:28:13Z
出版者: 2012 IEEE International Conference on Systems Biology (ISB)
摘要: Abstract:RNA-seq data analysis not only detects novel transcripts, promoters, and single nucleotide polymorphisms in a transcriptome scale, but also shows quantitative measurement of gene expression. In order to perform differential expression analysis for unraveling biological functions, we proposed a workflow which integrated annotations from KEGG biological pathways and Gene Ontology associations for manipulating multiple RNA-seq datasets. The developed system started from mapping short reads onto reference genes, and then performed normalization procedures on read coverage to evaluate and compare expression levels within various gene clusters. Different levels of gene expression were indicated by diverse color shades and graphically shown in designed temporal pathways. Besides, representative GO terms associated with differentially expressed gene cluster were also visually displayed by a GO tag cloud representation. Three different public RNA-seq datasets were applied to demonstrate that the proposed workflow could provide effective and efficient analysis on differential gene expression for either cross-strain comparison or an identical sample sequenced at different time points.
URI: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/44265
显示于类别:[資訊工程學系] 演講及研討會

文件中的档案:

档案 描述 大小格式浏览次数
index.html0KbHTML21检视/开启


在NTOUR中所有的数据项都受到原著作权保护.

 


著作權政策宣告: 本網站之內容為國立臺灣海洋大學所收錄之機構典藏,無償提供學術研究與公眾教育等公益性使用,請合理使用本網站之內容,以尊重著作權人之權益。
網站維護: 海大圖資處 圖書系統組
DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈