English  |  正體中文  |  简体中文  |  Items with full text/Total items : 26988/38789
Visitors : 2343927      Online Users : 38
RC Version 4.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Adv. Search
LoginUploadHelpAboutAdminister

Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/44258

Title: Exclusive Genomic Pathway Analysis for Groupers Infected by Different Iridovirus
Authors: Chun-Cheng Liu
Chien-Ming Chen
Tun-Wen Pai
Hsin-Yiu Chou
Hui-Huang Hsu
Contributors: 國立臺灣海洋大學:資訊工程學系
NTOU:Department of Computer Science and Engineering
Keywords: RNA-Seq
groupers
iridovirus
pathway
Date: 2015-07
Issue Date: 2017-11-20T07:57:53Z
Publisher: The 9th International Conference on Complex, Intelligent, and Software Intensive Systems (CISIS 2015)
Abstract: Abstract:Grouper is one of the most important aquaculture fish in the world. Due to high density of grouper farming, the aquaculture industry is threatened by iridovirus infections in recent years. In this study, we used next-generation sequencing technologies to analyze gene differential expression of groupers infected by two different types of iridoviruses, including Grouper Iridovirus of Taiwan (TGIV) of Megalocytivirus and Grouper Iridovirus (GIV) of Ranavirus. Zebra fish (Danio rerio) was selected as the reference model for gene functional annotations and pathway analyses. According to different fold change levels and identified associated KEGG pathways from defined gene sets, we found exclusive biological characteristics of groupers infected by two different iridoviruses. The results have shown that two specific gene sets, including the first set of PSMB2, CASP3, and U2AF2 for TGIV and the second set of PTGES, PDE3, and THBS1 for GIV were significantly and exclusively expressed. Furthermore, we also found two important pathways, Proteasome and ECM-receptor interaction pathways, were identified by employing gene set/pathway enrichment analysis. These results could facilitate biologists realizing comprehensive gene regulation of groupers infected by different iridoviruses and developing specific vaccines for grouper aquaculture.
URI: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/44258
Appears in Collections:[資訊工程學系] 演講及研討會

Files in This Item:

File Description SizeFormat
index.html0KbHTML35View/Open


All items in NTOUR are protected by copyright, with all rights reserved.

 


著作權政策宣告: 本網站之內容為國立臺灣海洋大學所收錄之機構典藏,無償提供學術研究與公眾教育等公益性使用,請合理使用本網站之內容,以尊重著作權人之權益。
網站維護: 海大圖資處 圖書系統組
DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback