Abstract:Atrazine, 2-chloro-4-(ethyl amino)-6-(isopropyl amino)-s-triazine, is a widely used herbicide for the control of grass and broad leaf weeds in crops such as sorghum, maize, sugarcane, lupins, pine and eucalyptus was plantations. Therefore, this study was designed to determine the protective effect of P. alba and C. halicacabum on atrazine induced oxidative liver injury in albino rats. Thirty male rats were divided into five groups of 6 animals each. Changes in liver dys function parameters represented by SOD, CAT, GSH and LPO were determined in liver as indicators of oxidative damage. Meanwhile atrazine administration decreased SOD, CAT and GSH in animals. In addition liver LPO level was increased. Liver histological studies have confirmed the changes observed in enzymological parameters and proved the beneficial role of P. alba and C. halicacabum. With P. alba or C. halicacabum administration during intoxication of atrazine, corrective effects on atrazine induced oxidative stress in the liver have been observed, while P. alba and C. halicacabum together assured a more efficient protection of the organ against the noticed oxidative stress.