National Taiwan Ocean University Institutional Repository:Item 987654321/40167
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 28611/40649
造访人次 : 625121      在线人数 : 76
RC Version 4.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 进阶搜寻

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/40167

题名: Ecological genomics in Xanthomonas: the nature of genetic adaptation with homologous recombination and host shifts
作者: Chao-Li Huang;Pei-Hua Pu;Hao-Jen Huang;Huang-Mo Sung†, Hung-Jiun Liaw†, Yi-Min Chen;Chien-Ming Chen;Ming-Ban Huang;Naoki Osada;Takashi Gojobori;Tun-Wen Pai;Yu-Tin Chen;Chi-Chuan Hwang;Tzen-Yuh Chiang
贡献者: 國立臺灣海洋大學:資訊工程學系
日期: 2015
上传时间: 2017-01-16T02:44:22Z
出版者: BMC Genomics
摘要: Abstract: Background
Comparative genomics provides insights into the diversification of bacterial species. Bacterial speciation usually takes place with lasting homologous recombination, which not only acts as a cohering force between diverging lineages but brings advantageous alleles favored by natural selection, and results in ecologically distinct species, e.g., frequent host shift in Xanthomonas pathogenic to various plants.

Results
Using whole-genome sequences, we examined the genetic divergence in Xanthomonas campestris that infected Brassicaceae, and X. citri, pathogenic to a wider host range. Genetic differentiation between two incipient races of X. citri pv. mangiferaeindicae was attributable to a DNA fragment introduced by phages. In contrast to most portions of the genome that had nearly equivalent levels of genetic divergence between subspecies as a result of the accumulation of point mutations, 10% of the core genome involving with homologous recombination contributed to the diversification in Xanthomonas, as revealed by the correlation between homologous recombination and genomic divergence. Interestingly, 179 genes were under positive selection; 98 (54.7%) of these genes were involved in homologous recombination, indicating that foreign genetic fragments may have caused the adaptive diversification, especially in lineages with nutritional transitions. Homologous recombination may have provided genetic materials for the natural selection, and host shifts likely triggered ecological adaptation in Xanthomonas. To a certain extent, we observed positive selection nevertheless contributed to ecological divergence beyond host shifting.

Conclusion
Altogether, mediated with lasting gene flow, species formation in Xanthomonas was likely governed by natural selection that played a key role in helping the deviating populations to explore novel niches (hosts) or respond to environmental cues, subsequently triggering species diversification.
關聯: 161(88)
URI: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/40167
显示于类别:[資訊工程學系] 期刊論文

文件中的档案:

档案 描述 大小格式浏览次数
index.html0KbHTML89检视/开启


在NTOUR中所有的数据项都受到原著作权保护.

 


著作權政策宣告: 本網站之內容為國立臺灣海洋大學所收錄之機構典藏,無償提供學術研究與公眾教育等公益性使用,請合理使用本網站之內容,以尊重著作權人之權益。
網站維護: 海大圖資處 圖書系統組
DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈