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Title: Cytotoxic neolignans: an SAR study
Authors: Zwe-Ling Kong, Shin-Cheng Tzeng, Yeuk-Chuen Liu
Contributors: 國立臺灣海洋大學:食品科學系
Keywords: SAR
Date: 2005
Issue Date: 2017-01-16T01:08:06Z
Publisher: Bioorganic & Medicinal Chemistry Letters
Abstract: Abstract
The neolignans, magnolol 1 and honokiol 2 have been reported to inhibit the growth of several tumor cell lines in vitro and in vivo. The chemical structure of magnolol and honokiol consists of biphenyl skeleton with phenolic and allylic functionalities. Analogs of 1 and 2 containing different substitution have been studies for their effect on the growth of Hep-G2 and their structure–activity relationships were reported in this work.
Relation: 15(1)
Appears in Collections:[Department of Food Science] Periodical Articles

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