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Title: Identification of cyprinol and cyprinol sulfate from grass carp bile and their toxic effects in rats
Authors: Deng-Fwu Hwang
Yen-Hung Yeh
Yi-Show Lai
Jou-Fang Deng
Contributors: 國立臺灣海洋大學:食品科學系
Keywords: Toxicity
Grass carp bile
Cyprinol sulfate
Date: 2001-02
Issue Date: 2016-11-23T02:31:42Z
Publisher: Toxicon
Abstract: Abstract: To elucidate the responsible toxic components of grass carp bile, the bile salt 5α-cyprinol sulfate and its desalted form 5α-cyprinol from grass carp bile were purified and identified by analyses of infrared spectrum, 1H-, 13C-nuclear magnetic resonance spectra and mass spectrum. The toxicity of grass carp bile powder, butanol extract of grass carp bile powder, 5α-cyprinol and 5α-cyprinol sulfate in rats were further determined. The kidney and liver functions were significantly affected by grass carp bile powder, butanol extract and 5α-cyprinol sulfate. However, 5α-cyprinol also significantly affected the kidney function, but the toxic effect was less.
Relation: 39(2)
Appears in Collections:[Department of Food Science] Periodical Articles

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