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Title: Evaluation of food safety for glucosamine in male Wistar rats and investigation of label and quality of commercial chitinous products
Authors: Deng-Fwu Hwang
Chiu-Yen Chung
Lang-Bang Hung
Contributors: 國立臺灣海洋大學:食品科學系
Keywords: Heavy metal
Food safety
Date: 2010-12
Issue Date: 2016-11-10T07:31:47Z
Publisher: 臺灣水產學會刊
Abstract: ABSTRACT: The applications of chitinous products have been developed to use as healthy food or food additive
in the world. To certify the edible safety of chitin monomer glucosamine for human, the animal test was
then carried out. The male Wistar rats were fed diets with different levels (0.25-10%) of glucosamine for 8
weeks. The results indicated that glucosamine showed no harmful effects on the growth, blood characters,
and biological functions of liver and kidney with any level. However, more than 0.25% glucosamine
could reduce the behavior activity, the levels of plasma glucose and creatinine, and the activity of plasma
creatine kinase in the rats, but increase level of plasma insulin in rats. These indicators are more
efficacies when the rats were fed diet with glucosamine sulfate than glucosamine HCl. Furthermore, 21
commercial chitinous samples were examined for heavy metal contents, degree of deacetylation and
glucosamine content. It was found that Zn and Fe might contaminate the chitinous samples, ranging <10
ppb - 101 ppm and <10 ppb - 1,020 ppm, respectively. Except one sample (less than 1%), the degree of
deacetylation in the commercial chitinous products ranged 43-98%. The amount of glucosamine ranged
from 1 mg/g to 864 mg/g. It means the quality and heavy metal residue need to control for commercial
chitinous products.
Relation: 38(1)
URI: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/38819
Appears in Collections:[食品科學系] 期刊論文

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