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Title: Biomaterial availability of magnesium substituted beta-tricalcium phosphate converted from sea urchin Tripneustes gratilla shell
Authors: Yu-Chun Chen;Hsiao-Ya Huang;Hsiu-Mei Lin;Fu-Yin Hsu;Yu-Ping Su;Deng-Fwu Hwang
Contributors: 國立台灣海洋大學:生命科學系
Date: 2015-06
Issue Date: 2016-05-09T01:31:03Z
Publisher: Journal of the Ceramic Society of Japan
Abstract: Abstract:Sea urchinTripneustes gratillais one of the valuablefishery products in Taiwan. The edible part of sea urchin is about 10%and the rest is regarded as waste. In this study, sea urchin shell was used here as an ingredient to synthesize magnesiumsubstituted beta-tricalcium phosphate (¢-TCMP). Shell powder of the echinoidTripneustes gratillawas converted byhydrothermal reaction at 180°C for 24 h (referred as SU-180-24 product), and calcinated into tablet at 800°C for 4 h to formthe target ingredient (SU-800-4 product). Then these products were tested for chemical composition analysis and bioassays. Theseproducts are confirmed to be rich in magnesium and constitute as¢-TCMP. Results from bioassays showed that SU-180-24 andSU-800-4 products increased cell viability in human osteosarcoma cell (MG-63). Alkaline phosphatase (ALP) activity of MG-63cell cultured with SU-800-4 tablet also showed significant increase when compared to commercial¢-TCMP. It indicated that seaurchin’s¢-TCMP materials including SU-180-24 and SU-800-4 products exhibited the potential for applying as the bone graftmaterial.
Relation: 123(1438),pp.469-475
Appears in Collections:[Department of Life Science] Periodical Articles

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