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Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/37482

Title: Polyoxygenated Sterols from Freshwater Clam
Authors: Zwe-Ling Kong;Siauo Chi Yu;Shu Ai Dai;Cha-Chung Tu;Min-Hsiung Pan;Yeuk-Chuen Liu
Contributors: 國立臺灣海洋大學:食品科學系
Keywords: Freshwater clam;Sterols;Cytotoxic activity;Corbicula fluminea
Date: 2011
Issue Date: 2016-03-07T02:26:10Z
Publisher: Helvetica Chimica Acta
Abstract: Abstract:Two new biologically active polyoxygenated sterols, 3,5,9-trihydroxycholest-7-en-6-one (1) and cholest-7-ene-3,6,9-triol (3), together with one known sterone, topsentisterol D3 (2), were isolated from freshwater clam (Corbicula flumineamuller; an important cultured edible shellfish in Taiwan). The structure elucidation of sterols 1–3 were accomplished by 1H- and 13C-NMR, HMQC, and HMBC, and MS analyses. The sterols 1–3 displayed cytotoxicities against the human hepatoma Hep G2 cells (IC50: 6.04±0.07, 40.78±4.28, and 10.57±0.51 μg/ml, resp.).
Relation: 94(5),pp.894-896
URI: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/37482
Appears in Collections:[食品科學系] 期刊論文

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