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Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/30328

Title: 製作金顆粒附著奈米銀膜之表面電漿共振生物晶片
Fabrication of surface plasmon resonance biochip composed of Au nanoparticles over Ag nanofilms
Authors: Guo-Wei Lee
李國瑋
Contributors: NTOU:Institute of Optoelectronic Sciences
國立臺灣海洋大學:光電科學研究所
Keywords: 表面電漿
surface plasmon
Date: 2011
Issue Date: 2011-11-25T07:39:57Z
Abstract: 本論文目的是探討利用熱蒸鍍的方式製作 金奈米顆粒/銀膜(50nm) 奈米結構之表面電漿共振(SPR)生物晶片,在量測方面是利用表面電漿共振外差干涉式相位量測系統,針對不同折射率葡萄糖溶液量測表面電漿共振生物晶片之相位靈敏度。(1)在入射波長為632.8nm時,改變多種不同蒸鍍參數,我們可以獲得 金奈米顆粒(1nm)/銀膜(50nm) 有最佳靈敏度2.8x10-7 RIU;(2)改變多個不同入射波長,我們可以獲得 金奈米顆粒(1nm)/銀膜(50nm) 在入射波長945nm時有最佳靈敏度1.28x10-7 RIU;(3)我們將 金奈米顆粒(1nm)/銀膜(50nm)/鉻膜(5nm) 三層奈米結構之生物晶片應用在即時量測上。
The goal of this thesis is to study the sensitivity of surface plasmon resonance (SPR) biochip with gold nanoparticles over silver thin film (50nm) nanostructures fabricated by thermal evaporation. The detection sensitivity of biochip with gold nanoparticles over silver thin film for different refractive index of glucose solution can be observed by SPR heterodyne interferometry phase interrogation system. The first case, size of gold nanoparticles over silver thin film can be tuned by controlling deposition parameters of thermal evaporation. At the incident wavelength of 632.8nm, the optimal sensitivity, down to 2.8x10-7 refractive index units (RIU) can be achieved, by employing the gold nanoparticles (1nm) over silver thin film (50nm) nanostructures biochip. The second case, the sensitivity can be changed via multi-wavelength of incident light. At the incident wavelength of 945nm, the optimal sensitivity, down to 1.28x10-7 RIU can be achieved, by employing the gold nanoparticles (1nm) over silver thin film (50nm) nanostructures biochip. The third case, surface plasmon resonance biochip with gold nanoparticles (1nm)/silver thin film (50nm)/chromium thin film (5nm) nanostructures can be applied to real-time measurement.
URI: http://ethesys.lib.ntou.edu.tw/cdrfb3/record/#G0M98880023
http://ntour.ntou.edu.tw/handle/987654321/30328
Appears in Collections:[光電科學研究所] 博碩士論文

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