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题名: Lymphocytes Estimation and Control Strategy of a Biodynamical Model of HIV-1
作者: Cheng-Fa Cheng;Ching-Yuan Cheng
贡献者: NTOU:Department of Communications Navigation and Control Engineering
关键词: Biodynamical model;Feedback control;Stability region estimation;T-S fuzzy model;Unknown equilibrium
日期: 2008
上传时间: 2011-10-21T02:36:07Z
出版者: 2008 International Automatic Control Conference
摘要: Abstract:The problems of stability regions estimation, observer design, and adaptive feedback control for a class of the continuous differential equation models of the interaction dynamics of HIV-1 and CD4 and CD8 lymphocytes in the human body are investigated. First, the output feedback control law is derived such that in the closed-loop system, the states that represent CD4, CD8 and viral load, can be regulated to a specified equilibrium point in the state space. The stabilizing controller is analogous to require only finite and little therapeutic drug regimen. Furthermore, since the CD4 and CD8 populations in a human have a typical range of equilibrium values, a T-S fuzzy model will be employed to monitor the lymphocyte counts. Finally, due to the exact information about the equilibrium may not be available, we will propose a linear adaptation law and examine the conditions under which it achieves the stabilization of the unknown equilibrium.
显示于类别:[通訊與導航工程學系] 演講及研討會





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