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Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/28180

Title: Lymphocytes Estimation and Control Strategy of a Biodynamical Model of HIV-1
Authors: Cheng-Fa Cheng;Ching-Yuan Cheng
Contributors: NTOU:Department of Communications Navigation and Control Engineering
Keywords: Biodynamical model;Feedback control;Stability region estimation;T-S fuzzy model;Unknown equilibrium
Date: 2008
Issue Date: 2011-10-21T02:36:07Z
Publisher: 2008 International Automatic Control Conference
Abstract: Abstract:The problems of stability regions estimation, observer design, and adaptive feedback control for a class of the continuous differential equation models of the interaction dynamics of HIV-1 and CD4 and CD8 lymphocytes in the human body are investigated. First, the output feedback control law is derived such that in the closed-loop system, the states that represent CD4, CD8 and viral load, can be regulated to a specified equilibrium point in the state space. The stabilizing controller is analogous to require only finite and little therapeutic drug regimen. Furthermore, since the CD4 and CD8 populations in a human have a typical range of equilibrium values, a T-S fuzzy model will be employed to monitor the lymphocyte counts. Finally, due to the exact information about the equilibrium may not be available, we will propose a linear adaptation law and examine the conditions under which it achieves the stabilization of the unknown equilibrium.
URI: http://ntour.ntou.edu.tw/handle/987654321/28180
Appears in Collections:[通訊與導航工程學系] 演講及研討會

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