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Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/27865

Title: REMUS: a tool for identification of unique peptide segments as epitopes
Authors: Tun-Wen Pai;Margaret Dah-Tsyr Chang;Wen-Shyong Tzou;Bo-Han Su;Pei-Chih Wu;Hao-Teng Chang;Wei-I Chou
Contributors: NTOU:Department of Computer Science and Engineering
Keywords: unique peptide;epitope orediction;physical-chemical preperty;secondary structure element
Date: 2006-07-01
Issue Date: 2011-10-21T02:34:16Z
Publisher: Nucleic Acids Research
Abstract: Abstract:We provide a ‘REMUS’ (reinforced merging techniques for unique peptide segments) web server for identification of the locations and compositions of unique peptide segments from a set of protein family sequences. Different levels of uniqueness are determined according to substitutional relationship in the amino acids, frequency of appearance and biological properties such as priority for serving as candidates for epitopes where antibodies recognize. REMUS also provides interactive visualization of 3D structures for allocation and comparison of the identified unique peptide segments. Accuracy of the algorithm was found to be 70% in terms of mapping a unique peptide segment as an epitope. The REMUS web server is available at http://biotools.cs.ntou.edu.tw/REMUS and the PC version software can be freely downloaded either at http://bioinfo.life.nthu.edu.tw/REMUS or http://spider.cs.ntou.edu.tw/BioTools/REMUS. User guide and working examples for PC version are available at http://spider.cs.ntou.edu.tw/BioTools/REMUS-DOCS.html, and details of the proposed algorithm can be referred to the documents as described previously.
Relation: 34(2), pp.W198-W201
URI: http://ntour.ntou.edu.tw/handle/987654321/27865
Appears in Collections:[生命科學暨生物科技學系] 期刊論文
[資訊工程學系] 期刊論文

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