English  |  正體中文  |  简体中文  |  Items with full text/Total items : 26988/38789
Visitors : 2315865      Online Users : 34
RC Version 4.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Adv. Search
LoginUploadHelpAboutAdminister

Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/27796

Title: Discover Significant Associations of Orthologous Simple Sequence Repeat Patterns with Gene Ontology Terms
Authors: Chien-Ming Chen;Chia-Sheng Chuang;Zhen-Li Huang;Tun-Wen Pai
Contributors: NTOU:Department of Computer Science and Engineering
國立臺灣海洋大學:資訊工程學系
Keywords: Comparative Genomics;Gene Ontology;Homologous Gene;Simple Sequence Repeat
Date: 2009
Issue Date: 2011-10-21T02:34:02Z
Publisher: 2009 IEEE International Conference on Bioinformatics and Biomedicine Workshops
Abstract: Abstract:Several simple sequence repeats (SSRs) have been demonstrated to regulate gene functions, and SSR mutations in a disease gene may cause different genetic disorders. In order to identify putative functional SSR patterns, a Web system for discovering significant associations between SSR motifs and gene ontology (GO) terms was developed in this study. The system is named as GOSH: Gene Ontology SSR Hierarchy. GOSH employed the GO hierarchy term structure to facilitate users to select a functional or biological gene subset. Significant SSR patterns can be retrieved and identified by a comprehensive over representation analysis within a target gene subset and comparing the results with orthologous genes. Pattern relationship between different biological subsets or supersets can be observed by GO hierarchy structure directly. GOSH also supports gene ontology search through identified significant SSR patterns, and all GO terms possessing specific significant SSR patterns are listed for referencing. The proposed GOSH system is the first comprehensive and efficient online mining tool for discovering significant orthologous SSR patterns with gene ontology terms. The system is available at: http://gosh.cs.ntou.edu.tw.
Relation: pp.209-213
URI: http://ntour.ntou.edu.tw/handle/987654321/27796
Appears in Collections:[資訊工程學系] 演講及研討會

Files in This Item:

File Description SizeFormat
index.html0KbHTML291View/Open


All items in NTOUR are protected by copyright, with all rights reserved.

 


著作權政策宣告: 本網站之內容為國立臺灣海洋大學所收錄之機構典藏,無償提供學術研究與公眾教育等公益性使用,請合理使用本網站之內容,以尊重著作權人之權益。
網站維護: 海大圖資處 圖書系統組
DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback