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Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/27540

Title: SERS study of tetrodotoxin (TTX) by using silver nanoparticle arrays
Authors: Wen-Chi Lin;Hsiao-Chin Jen;Chang-Long Chen;Deng-Fwu Hwang;Railing Chang;Jih-Shang Hwang;Hai-Pang Chiang
Contributors: NTOU:Institute of Optoelectronic Sciences
國立臺灣海洋大學:光電科學研究所
Keywords: Surface enhaced Raman scattering (SERS);Tetrodotoxin (TTX);Nanosphere lithography (NSL);Ag nanoparticle arrays;Density functional theory (DFT)
Date: 2009-06-01
Issue Date: 2011-10-21T02:32:06Z
Publisher: Plasmonics
Abstract: Abstract:The optical properties of tetrodotoxin (TTX), a scarce toxin with anesthetic properties, were studied using nanoparticle arrays-assisted surface-enhanced Raman scattering (SERS). The nanoparticles arrays were fabricated using nanosphere lithography and a metallic lift-off process to control the particle size, shape, and spacing in the arrays. Using density functional methods, the Raman spectrum of TTX was also calculated with Gaussian03 software. The main peaks of the spectrum are originated from the vibration of the NH2 molecule group. In the SERS experiment, we were able to measure the Raman spectrum with a TTX concentration as less as 0.9 ng/mL. This sensitivity is comparable to that from high performance liquid chromatography.
Relation: 4(2), pp.187-192
URI: http://ntour.ntou.edu.tw/handle/987654321/27540
Appears in Collections:[光電科學研究所] 期刊論文

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