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Please use this identifier to cite or link to this item: http://ntour.ntou.edu.tw:8080/ir/handle/987654321/26995

Title: An in vivo study of a bone grafting material consisting of hydroxyapatite and reconstituted collagen
Authors: Fu-Yin Hsu;Shiao-Wen Tsai;Chen-Wen Lan;Yng-Jiin Wang
Contributors: NTOU:Institute of Bioscience and Biotechnology
Keywords: collagen;hydroxyapatite
Date: 2005-04-01
Issue Date: 2011-10-21T02:22:13Z
Publisher: Journal of Materials Science: Materials in Medicine
Abstract: Abstract:This study aims to evaluate the performance of our recently developed microspheres of hydroxyapatite/reconstituted collagen as a bone grafting material. The microspheres were fabricated into a circular disc and implanted in a pre-drilled hole in a rat’s calvaria. The bone tissue had regenerated and grown into the disc bone graft 4 weeks following implantation. After 16 weeks of implantation, the regenerated bone had integrated with the remaining material and made close contact with it. The disc had been completely absorbed with almost no visible bone graft left after 24 weeks of implantation. In contrast, a hydroxyapatite disc still remained intact on the 24th week after implantation. These results suggested that the hydroxyapatite/reconstituted collagen microsphere can be used as an excellent bone grafting material.
Relation: 16(4), pp.341-345
URI: http://ntour.ntou.edu.tw/handle/987654321/26995
Appears in Collections:[生命科學暨生物科技學系] 期刊論文

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